In the latest sign that government-run health care passage hasn’t helped Democrats in the lead-up to November, a new poll released by Quinnipiac University shows conservative Pat Toomey (R) taking a five-point lead over incumbent Senator Arlen Specter (D), who has the backing of the Obama Administration.

In fact, that’s not the only good news for Republicans in Pennsylvania. Other candidates on the right have benefited from the unpopular agenda pushed by Democrats.

Republican Pat Toomey is back on top 46 – 41 percent over Sen. Arlen Specter in Pennsylvania’s seesaw U.S. Senate race, while Attorney General Tom Corbett, the leader for the Republican gubernatorial nomination, remains ahead of each of the three top Democratic contenders by double digits, according to a Quinnipiac University poll released today.

Barack Obama’s approval rating in the usually-blue state? In negative territory. Just 45% approve while 49% disapprove of his job performance. Obama carried Pennsylvania by a margin of about 55-44 in the last presidential election.

What’s driving this unpopularity? Say hello to voter backlash for government-run health care.

Disapproval of the President’s health care plan, 53 – 39 percent, is unchanged from a 52 – 37 percent disapproval March 2. Pennsylvania voters say 39 – 20 percent they are more likely to vote against a lawmaker who supported the health plan.

So what happens if Arlen Specter is successfully challenged by Rep. Joe Sestak (D-PA), who has accused the White House of violating federal law by offering him a high-ranking job in exchange for dropping out of the race? Even if Sestak is the nominee, Toomey — the conservative Republican — wins.

Toomey also leads U.S. Rep. Joe Sestak, who is challenging Specter in the Democratic primary, by 42 – 34 percent. Specter leads Sestak for the Democratic nomination 53 – 32 percent in a Quinnipiac University poll released yesterday of likely Democratic primary voters, a different sample.

So a conservative Republican is set to defeat both the liberal challenger and multi-term liberal incumbent in blue Pennsylvania. And another Republican is set to defeat all three top Democratic contenders in the gubernatorial race.

Heckuva job with that health care legislation, Barry.

More: The American Spectator, Hot Air, RedState.